"Quds Day is the day for the revival of the Palestinian rights, and end of occupation and settlements," Zarif wrote on his Twitter account on Friday.
"Israel is the largest human rights violator, the only holder of nuclear weapons in the region and the most serious chronic threat to international peace and security," he added.
The top Iranian diplomat pointed out that the conspiracy of the racist Deal of the Century proved that Washington is a partner to the aggressors and there is no hope for it.
"The referendum is the only solution," Zarif reiterated.
The International Quds Day is an annual event opposing Israel's occupation of Beitul-Muqaddas. Anti-Zionist rallies and demonstrations are held on the last Friday of Ramadan in Muslim and Arab countries around the world, specially in Iran, as well as a large number of non-Muslim states.
The International Quds Day was started by the late Founder of the Islamic Republic, Imam Khomeini, in 1979 as a way of expressing solidarity with the Palestinians and underscoring importance of the holy Quds to Muslims.
Due to the outbreak of coronavirus in Iran, the International Quds Day will be commemorated differently without holding gatherings and rallies.